KALTENBOECK, BERNHARD,GUPTA, RAM B.,CHOWDHURY, ERFAN U.,OBER, COURTNEY A.
申请号:
CA2945925
公开号:
CA2945925A1
申请日:
2015.03.31
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Disclosed are compositions, kits, and methods for inducing an immune response against' an infection or a disease. The compositions typically include biodegradable particles having an average effective diameter of 0.5 - 20 µ??, and optionally the compositions include one or more of an adjuvant, an apopiosis inhibitor, and an antigen. The compositions, kits, and methods may be utilized to induce a cell-mediated response, such as a T- helper cell response., arid/or a humoral response against a pathogen or a disease. In some embodiments, the compositions, kits, and methods may be utilized to induce preferentially a Till response versus other types of immune responses such as a Th2 response.