SON, JIN RYUL,손진열,BACK, HYON HO,백현호,PARK, EUN HEE,박은희,LEE, SUNG WAN,이성완,SONG, MIN GYU,송민규,CHA, JA HYUN,차자현,CHA, JAE UK,차재욱,KO, WON HWA,고원화
申请号:
KR1020100103053
公开号:
KR1020120041554A
申请日:
2010.10.21
申请国别(地区):
KR
年份:
2012
代理人:
摘要:
PURPOSE: A composition for enteric soft capsules is provided to delay generation of salt reduction during storage.CONSTITUTION: A composition for an enteric soft capsule contains: 50-90 parts by weight of hydroxyl propyl methyl cellulose phthalate(HPMCP), 10-50 parts by weight of hydroxyl propyl methyl cellulose(HPMC), 5.5-8.5 parts by weight of alkaline agent, and 2-15 parts by weight of polyol with at least three hydroxyl groups. The alkaline agent includes ammonium, sodium hydroxide, potassium hydroxide, calcium hydroxide, or mixture of two or more ingredients. The polyol includes glycerin, sorbitol, triethanol amine, sucrose, or glycoside. The composition additionally contains 0.05-0.5 parts by weight of an emulsifier.COPYRIGHT KIPO 2012장용성 경질 캡슐용 조성물 및 상기 조성물을 사용하여 제조된 장용성 경질 캡슐이 개시된다. 개시된 장용성 경질 캡슐용 조성물은 적어도 3개의 히드록시기를 갖는 폴리올을 포함한다. 개시된 장용성 경질 캡슐은 보관시 염 석출 현상의 발생이 지연된다.