BEAN ANDREW,LOWENTHAL JOHN WILLIAM,MALAVER ORTEGA LUIS FERNANDO,TRIPP RALPH A
申请号:
IN201817020963
公开号:
IN201817020963A
申请日:
2018.06.05
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention relates to methods of replicating viruses in vitro. In particular the invention relates to a genetically modified population of cells and/or a population of cells treated with an exogenous compound wherein the cells are capable of producing more virus than cells lacking the genetic modification and/or lacking treatment with the exogenous compound. The invention also relates to methods of producing populations of such cells as well as the use of the viruses obtained to prepare vaccine compositions.