Commonwealth Scientific and Industrial Research Organisation;University of Georgia Research Foundation, Inc.
发明人:
Andrew Bean,John William Lowenthal,Luis Fernando Malaver-Ortega,Ralph A. Tripp
申请号：
US16258229
公开号：
US20190322989A1
申请日:
2019.01.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to methods of replicating viruses in vitro. In particular, the invention relates to a genetically modified population of cells, and/or a population of cells treated with an exogenous compound, wherein the cells are capable of producing more virus than cells lacking the genetic modification and/or lacking treatment with the exogenous compound. The invention also relates to methods of producing populations of such cells, as well as the use of the viruses obtained to prepare vaccine compositions.
