Laurie Ellen Kilpatrick;Clifford S. Deutschman;Helen Marie Korchak
发明人:
Laurie Ellen Kilpatrick,Helen Marie Korchak,Clifford S. Deutschman
申请号:
US12488954
公开号:
US08470766B2
申请日:
2009.06.22
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides novel formulations of a δPKC inhibitor. The δPKC inhibitor can be, for example, a peptide. The present invention also discloses a method of preventing acute pulmonary cell injury associated with trauma, ALI or ARDS and a method of inhibiting an inflammatory response in pulmonary cells by inhibiting the activity of δPKC. The invention also provides a method of treating a pulmonary disease with an aerosol formulation of a δPKC inhibitor to inhibit neutrophil activity.