您的位置: 首页 > 农业专利 > 详情页

ANTICORPO ANTI-INTEGRINA-ALFA9 HUMANA HUMANIZADO MELHORADO
专利权人:
ASTELLAS PHARMA INC.
发明人:
TOSHIHIRO NAKASHIMA,KENJI UEHARA,HIROFUMI HIGUCHI,DAISUKE ISHIKAWA,NOBUCHIKA YAMAMOTO,HIROTADA FUJITA,FUMIHIKO SAKAI
申请号:
PT09700904
公开号:
PT2243829E
申请日:
2009.01.09
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The present invention provides a humanized anti-human ±9 integrin antibody having improved activity and/or property as compared to donor mouse anti-human ±9 integrin antibody, namely, a humanized anti-human ±9 integrin antibody comprising a heavy-chain variable region consisting of the amino acid sequence shown by SEQ ID NO: 1 or the amino acid sequence shown by SEQ ID NO: 1 wherein one or several amino acids are substituted, deleted, inserted and/or added and a light-chain variable region consisting of the amino acid sequence shown by SEQ ID NO: 61 or the amino acid sequence shown by SEQ ID NO: 61 wherein one or several amino acids are substituted, deleted, inserted and/or added, as well as a means for preventing or treating various diseases involving human ±9 integrin in their pathogenesis, which uses the antibody.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充