Antibody-drug conjugate

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专利权人:

DAIICHI SANKYO COMPANY LIMITED

发明人:

Masuda, Takeshi,Naito, Hiroyuki,Nakada, Takashi,Yoshida, Masao,Ashida, Shinji,Miyazaki, Hideki,Kasuya, Yuji,Morita, Koji,Abe, Yuki,Ogitani, Yusuke

申请号：

NZ70539413

公开号：

NZ705394A

申请日:

2013.10.10

申请国别(地区):

NZ

年份:

2018

代理人:

摘要：

Provided is an antibody-drug conjugate which can be used as an anti-tumor agent, said conjugate being characterized by being produced by binding an anti-tumor compound represented by formula (1) to an antibody through a linker having a structure represented by the formula: -L1-L2-LP-NH-(CH2)n1-La-Lb-Lc- (wherein the antibody is bound at the terminal of L1, and the anti-tumor compound is bound at the terminal of Lc in which the binding site of the anti-tumor compound is a nitrogen atom in an amino group located at position-1).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/