An ultrasound observation device includes a processor including hardware, the processor being configured to: generate an ultrasound image containing a transducer region based on an ultrasound signal received from an ultrasound transducer configured to emit ultrasound to an observation target and receive the ultrasound reflected on the observation target； cause a display to display the ultrasound image； receive a command input to move a region of interest set in the ultrasound image； and move, when a movement vector having a moving direction and a moving amount based on the command input passes through a predetermined region containing at least the transducer region in the ultrasound image, the region of interest to a discontinuous position on an opposite side with the transducer region interposed in the moving direction.
