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AUTOMATIC SYSTEM FOR SYNTHESIZING 123I-MIBG AND AUTOMATIC DEVICE FOR SYNTHESIZING AND DISPENSING 123I-MIBG COMPRISING THE SAME
专利权人:
发明人:
Tsai-Yueh LUO,Te-Sheng LIANG,Ying-Hsia SHIH,Wuu-Jyh LIN
申请号:
US14464461
公开号:
US20150056105A1
申请日:
2014.08.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to an automatic system for synthesizing iodine-123 meta-iodobenzylguanidine (123I-MIBG), which comprises a first reactor for subjecting radioactive iodine-containing sodium iodide and meta-iodobenzylguanidine (MIBG) sulfate to an iodine-iodine exchange reaction to obtain radioactive iodine labeled MIBG a purification unit for purifying the iodine labeled MIBG and a second reactor for substituting a solvent used in purification with a phosphate buffer to obtain a phosphate solution containing 123I-MIBG. The present invention also relates to an automatic device for dispensing 123I-MIBG, which comprises the automatic system for synthesizing 123I-MIBG, a radioactivity measuring unit, and a dispensing and packing unit.
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