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Methods and compositions for achieving hemostasis and stable blood clot formation
专利权人:
Inc.;Endomedix
发明人:
Piyush Modak,Malavika Nadig,Richard Russo
申请号:
US16194917
公开号:
US10517988B1
申请日:
2018.11.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided is tunable biopolymer hydrogel produced from two processed natural polysaccharides for use as a hemostat. If desired, the hydrogel formation can be tuned so that the hydrogel forms within seconds when applied to a tissue lesion. The resulting hydrogel can adhere to tissue and, without swelling, produce hemostasis within seconds after application to tissue of interest. The hydrogel also captures, aggregates and concentrates platelets and red blood cells at the site of the tissue lesion thereby initiating a clotting cascade at the site of the lesion. The hemostat can be used to prevent blood loss during surgical procedures, for example, during brain, spine or other surgical procedures where hemostasis is desirable, and is particularly useful during surgical procedures where swelling of the hemostat (e.g., in the brain or spine) would be detrimental to the subject.
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