THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
Gerard Karsenty,Patricia F. Ducy
申请号:
US14032008
公开号:
US09746463B2
申请日:
2013.09.19
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to methods and compositions for treating and diagnosing disorders related to energy metabolism and the OST-PTP signaling pathway involving gamma-carboxylase, osteocalcin and adiponectin. Such disorders include, but are not limited to, metabolic syndrome, glucose intolerance, diabetes types 1 and 2, atherosclerosis and obesity.