Michael Heartlein,Frank Derosa,Anusha Dias,Braydon Charles Guild
申请号：
US14775835
公开号：
US10087247B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides, among other things, methods and compositions for delivering an antibody in vivo by administering to a subject in need thereof one or more mRNAs encoding a heavy chain and a light chain of an antibody, and wherein the antibody is expressed systemically in the subject. In some embodiments, the one or more mRNAs comprise a first mRNA encoding the heavy chain and a second mRNA encoding the light chain of the antibody.
