Methods and compositions for delivering mRNA coded antibodies

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专利权人:

Inc.;Shire Human Genetic Therapies

发明人:

Heartlein, Michael,Derosa, Frank,Guild, Braydon Charles,Dias, Anusha

申请号：

AU2014239184

公开号：

AU2014239184A1

申请日:

2014.03.14

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention provides, among other things, methods and compositions for delivering an antibody in vivo by administering to a subject in need thereof one or more mRNAs encoding a heavy chain and a light chain of an antibody, and wherein the antibody is expressed systemically in the subject. In some embodiments, the one or more mRNAs comprise a first mRNA encoding the heavy chain and a second mRNA encoding the light chain of the antibody.

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中国工程科技知识中心

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http://www.ckcest.cn/home/