Tetrahydronaphthyridine and tetrahydropyrido[4,3-D]pyrimidine compounds and compositions thereof useful for the treatment of inflammatory and respiratory diseases

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专利权人:

Michael G. Kelly;Carl J. Kaub;John Kincaid

发明人:

Michael G. Kelly,John Kincaid,Carl J. Kaub

申请号：

US12660588

公开号：

US08859545B2

申请日:

2010.03.01

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Tetrahydronaphthyridine and tetrahydropyrido[4,3-d]pyrimidine compounds are disclosed that have formula 1:where A, B, L, N, R1, R3, R4′, Y and Z are as defined herein. The compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, respiratory conditions, and others.

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