NUCLEOSIDES ANALOGUES, THE USE THEREOF FOR PRODUCING MEDICAMENTS USEFUL AGAINST RETROVIRAL INFECTIONS AND HEPATITIS B VIRUS AND THE SAME MEDICAMENTS

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专利权人:

MEDIVIR AB

发明人:

ZHOU, XIAO-XIONG,JOHANSSON, NILS-GUNNAR,WAEHLING, HORST

申请号：

HU0100087

公开号：

HU228060B1

申请日:

1998.08.14

申请国别(地区):

HU

年份:

2012

代理人:

摘要：

A compound of the formula I <；CHEM>； wherein: nuc is the residue of a nucleoside analogue bonded through its single hydroxy group on the cyclic or acyclic saccharide moiety, R1 is hydroxy, amino or carboxy； optionally having esterified/amide bonded thereon a C4-C22 saturated or unsaturated, optionally substituted fatty acid or alcohol, or an aliphatic L-amino acid； R2 is the residue of an aliphatic L-amino acid； L1 is a trifunctional linker group； L2 is absent or a difunctional linker group； and pharmaceutically acceptable salts thereof. <；IMAGE>；

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