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Sigma receptor compounds
专利权人:
Laboratorios del Dr. Esteve S.A.
发明人:
CORBERA-ARJONA, Jordi,VANO-DOMENECH, David,HOLENZ, Joerg
申请号:
ES07723020
公开号:
ES2564418T3
申请日:
2007.03.02
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Compounds of general formula (I), ** Formula ** in which A represents an NR3 group; m is selected from 0, 1, 2; n is selected from 0, 1, 2, 3, 4; the dashed line ----- represents a single or double bond; R1 and R2, identical or different, represent a hydrogen atom; an optionally at least monosubstituted, linear or branched, saturated or unsaturated aliphatic radical; an optionally at least monosubstituted cycloalkyl group that is optionally condensed to other at least monosubstituted monocyclic or polycyclic ring systems; an optionally at least monosubstituted aryl group that is optionally condensed to other at least monosubstituted monocyclic or polycyclic ring systems; an optionally at least monosubstituted heterocyclyl group that is optionally fused to other at least monosubstituted monocyclic or polycyclic ring systems; an optionally at least monosubstituted, branched or unbranched, saturated or unsaturated alkyl-cycloalkyl group in which the cycloalkyl group is optionally at least monosubstituted and / or condensed with a monocyclic or polycyclic ring system; an optionally at least branched or unbranched alkyl-aryl alkyl group, saturated in which the aryl group may optionally be at least monosubstituted and / or condensed with a monocyclic or polycyclic ring system; an alkyl-heterocyclyl group optionally at least monosubstituted, branched or unbranched, saturated, wherein the heterocyclyl group may optionally be at least monosubstituted and / or condensed with a monocyclic or polycyclic ring system; a group (C>; = O) -R7; a group (C>; = O) -O-R7; a group (SOt) -R7; an NR7R7a group; a group (C>; = O) -NR7R7a; an O-R7 group; or together with the nitrogen atom forming a bridge, or form a heterocyclyl group containing at least one monocyclic heteroatom, optionally at least monosubstituted which is optionally condensed with a monocyclic or polycyclic ring system at least optionally monosubstituted and / or linked by groups linear alkylene and / or is optionall
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