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Cycloalkane derivative
专利权人:
Limited;Daiichi Sankyo Company
发明人:
SHINOZUKA, Tsuyoshi,KOBAYASHI, Hiroyuki,SUZUKI, Sayaka,TANAKA, Kyosuke,KIMOTO, Hiroko,DOMON, Yuki
申请号:
ES13746373
公开号:
ES2613078T3
申请日:
2013.02.08
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
A compound represented by formula (I) or a pharmacologically acceptable salt thereof: ** Formula ** in which each of Ar1 and Ar2 independently represents a heteroaryl group or an aryl group, each of R1, R2 and R3 represents independently a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a C1-C6 hydroxyalkyl group, a C1-C6 alkoxy-C1-C6 alkyl group, a C3- cycloalkyl group C7 or a cyano group, each of R4 and R5 independently represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a halogenated C1-C6 alkyl group, a hydroxyl group, a C1-C6 hydroxyalkyl group, a C1-C6 alkoxy-C1-C6 alkyl group, a C3-C7 cycloalkyl group or a C1-C6 alkoxy group and n represents an integer from 1 to 3, and in which the heteroaryl group or the aryl group optionally has one or two substituents independently selected from a halogen atom, an alkyl group or C1-C6, a halogenated C1-C6 alkyl group, a hydroxyl group, a C1-C6 hydroxyalkyl group, a C1-C6 alkoxy-C1-C6 alkyl group, a C3-C7 cycloalkyl group, a carboxy group, a cyano group , an amino group, a C1-C3 alkylamino group and a C1-C3 di-alkylamino group, and when the heteroaryl group or the aryl group has two such groups, the two groups are the same or different from each other.Un compuesto representado por la fórmula (I) o una sal farmacológicamente aceptable del mismo: **Fórmula** en la que cada uno de Ar1 y Ar2 representa independientemente un grupo heteroarilo o un grupo arilo, cada uno de R1, R2 y R3 representa independientemente un átomo de hidrógeno, un átomo de halógeno, un grupo alquilo C1-C6, un grupo alquilo C1-C6 halogenado, un grupo hidroxialquilo C1-C6, un grupo alcoxi C1-C6-alquilo C1-C6, un grupo cicloalquilo C3-C7 o un grupo ciano, cada uno de R4 y R5 representa independientemente un átomo de hidrógeno, un átomo de halógeno, un grupo alquilo C1-C6, un grupo alquilo C1-C6 halogenado, un grupo hidroxilo, un grupo hidroxialquilo C1-C6, un grupo alcoxi C1-C6-alquilo C1-C6, un grupo cicloa
来源网站:
中国工程科技知识中心
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