PHARMACEUTICAL COMPOSITION INCLUDING 5-{4-(AMINOSULFONYL)PHENYL}-2,2-DIMETHYL-4-(3-FLUOROPHENYL)-3(2H)-FURANONE AND CAPSULE FORMULATION INCLUDING THE PHARMACEUTICAL COMPOSITION
KIM, BYUNG-HA,AHN, SIK IL,PARK, JAE-YEON,KIM, TAE RYONG,CHO, JOONG MYUNG,RO, SEONGGU
申请号:
PH12016501445
公开号:
PH12016501445A1
申请日:
2016.07.21
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
The present invention relates to a pharmaceutical composition including (i) the compound of Formula 1 described in the specification or a pharmaceutically acceptable salt thereof, (ii) a pharmaceutically acceptable diluent, and (iii) a pharmaceutically acceptable lubricant. The compound of Formula 1 or pharmaceutically acceptable salt thereof has a 50 pcnt volume particle diameter (d(0.5)) of 3 mm to 9 mm. The pharmaceutical composition of the present invention has the advantages of good stability, high dissolution rate, improved content uniformity, and excellent pharmacokinetic properties. Due to these advantages, the pharmaceutical composition of the present invention is effective in treating inflammation or pain.