Antibodies binding to anionic phospholipids and aminophospholipids and their use in the preparation of pharmaceutical compositions for treating viral infections
BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM;PHILIP E. THORPE;MELINA M. SOARES;JIN HE
发明人:
PHILIP E. THORPE,MELINA M. SOARES,JIN HE
申请号:
IL19532808
公开号:
IL195328A
申请日:
2008.11.17
申请国别(地区):
IL
年份:
2014
代理人:
摘要:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.