METHODS OF TREATMENT USING MODULATORS OF SIRT2

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专利权人:

发明人:

Hening Lin,Bin HE

申请号：

US15172756

公开号：

US20160279091A1

申请日:

2016.06.03

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The instant application describes novel compounds that modulate (in particular, inhibit) Sirt2, with structures according to Formulas (1) and (2) provided herein. The invention is also directed to pharmaceutical compositions thereof, methods of treatment (i.e., cancer and neurodegenerative disease) by administration of the modulating compounds, assay methods for finding modulators of Sirt2, and kits for practicing the assay method.

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