An external fixation system for percutaneous drainage procedures may include a base. The base may include a first side. The first side may be positioned adjacent an exterior surface of a subject during use. The base may include a first coupler coupled to the first side of the base. The base may include a second side opposite the first side. The base may include an opening extending through the first coupler and the base such that the first coupler is in fluid communication with the second side of the base. The first coupler may be couplable to a conduit during use such that the conduit is in fluid communication with the second side of the base. In some embodiments, the second side of the base may include a second coupler configured to facilitate the attachment of a drainage bag or a mechanism to flush or evacuate a drainage catheter during use.