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MÉTHODES DE TRAITEMENT DE PATIENTS ATTEINTS DE SYNDROMES MYÉLODYSPLASIQUES
专利权人:
Actinium Pharmaceuticals; Inc.
发明人:
申请号:
EP18885506.8
公开号:
EP3720559A1
申请日:
2018.12.04
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Methods for treating a proliferative disease in hematologic malignancy in a subject having a complex karyotype by administering an effective amount of an immunotherapy which includes a targeting agent for an epitope of CD33. The proliferative disease may be a hematological disease or disorder such as multiple myeloma, acute myeloid leukemia, myelodysplastic syndrome, and myeloproliferative neoplasm. The effective amount of the anti-CD33 targeting agent may be an amount sufficient to induce myeloconditioning or an amount to induce myeloablation. The methods may further include transplanting allogeneic stem cells to the patient after administration of the anti-CD33 targeting agent.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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