Method for preparing a composition comprising an active ingredient particles combine with a Resin at a temperature higher than the melting point of the resin, Dispersing the combination in an oily medium and consolidate the dispersed particles.
ZHEN YUEQIAN,ZHANG SHILING,BECKER CHRISTIAN,YAN YUNFEI,CHEN YONGCHUN,SHI YUTIAN,KALANTAR THOMAS H.,YANG XIUHAN GRACE,TUCKER CHRISTOPHER JOHN
申请号:
CL2015000651
公开号:
CL2015000651A1
申请日:
2015.03.16
申请国别(地区):
CL
年份:
2015
代理人:
摘要:
Provided are compositions comprising a collection of coated particles, wherein the coated particles comprises an active ingredient dispersed in an resin matrix; and a coating comprising at least one hydrophobic compound. Also provided are methods for preparing compositions comprising: (a) blending an active ingredient (for example, 1-MCP complex powder) with resin at the temperature slightly over the melting point of the resin; (b) dispersing the blend into an oil medium containing hydrophobic particles by shearing and obtain an oil dispersion; and (c) consolidating the resin particles by cooling. Thus, the active ingredient (for example, 1-MCP complex powder) is imbedded in the resin matrix spheres, and the hydrophobic particles, which also serve as Pickering emulsifier to stabilize the matrix spheres, form a coating layer around the matrix spheres to provide protection against water. Thus, the sphere is composed of the “Pickering” particle and resin matrix, in which the active ingredient is imbedded.METODO PARA PREPARAR UNA COMPOSICION DE PARTICULAS QUE COMPRENDE COMBINAR UN INGREDIENTE ACTIVO CON UNA RESINA A UNA TEMPERATURA SUPERIOR AL PUNTO DE FUSION DE LA RESINA, DISPERSAR LA COMBINACION EN UN MEDIO OLEOSO Y CONSOLIDAR LAS PARTICULAS DISPERSAS.