Tad H. Koch,David J. Burkhart,Glen C. Post,Jordan W. Nafie,Brian T. Kalet,Benjamin L. Barthel,Daniel L. Rudnicki
申请号：
US12091321
公开号：
US08404650B2
申请日:
2006.10.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides therapeutically effective compounds for the prevention and treatment of cancer and pharmaceutical compositions containing these compounds as well as methods of using and administering these compounds. The invention also includes methods of activating a prodrug of these therapeutically effective compounds by the administration of a peptide-directed targeting construct that delivers a prodrug-activating enzyme to a target activation site.
