APTAMERES SPECIFIQUES AU FACTEUR XIA

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专利权人:

CANADIAN BLOOD SERVICES

发明人:

SHEFFIELD, WILLIAM PETER,DONKOR, DAVID APRAKU

申请号：

CA2966425

公开号：

CA2966425A1

申请日:

2017.05.04

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present disclosure concerns aptamers of formula (I) capable ofspecifically binding toFactor Xla. The aptamers can be used to prevent, treat or alleviate thesymptoms ofthrombosis. The aptamers can also be used to detect Factor Xla in a sampleand/or purifyFactor Xla from a sample. The aptamers can further be used to identityputative therapeuticagents for the prevention, treatment or alleviation of symptoms associatedwith thrombosis.

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