Liquid aqueous formulation, nasal drug dispensing device or dosage cartridge, and use of solubilizing agent.

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专利权人:

ARCHIMEDES DEVELOPMENT LIMITED

发明人:

PETER JAMES WATTS,YU-HUI CHENG

申请号：

BRPI0819115

公开号：

BRPI0819115A2

申请日:

2008.11.10

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention provides a liquid aqueous formulation for the intranasal administration of apomorphine, which comprises: (a) at least about 15 mg/ml of apomorphine； and (b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer)； (ii) at least one cyclodextrin； and (iii) at least one cyclodextrin together with chitosan. The formulations of the invention can be used in the treatment/management of Parkinson's disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/