Elyse Bourque,Bradford Hirth,Renato Sklerj,Elina Makino,Fazeela Morshed,Lingyun Li,Paul Mason,John P. Leonard,James Lillie,Hanlan Liu,Mary A. Cromwell,Bing Wang,Thomas O'Shea,Thomas OShea
申请号:
US14471958
公开号:
US09126993B2
申请日:
2014.08.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.