GRESHOCK, THOMAS J.,MULHEARN, JAMES,GUO, LIANGQIN,ZHANG, TING,WANG, DEPING,KIM, RONALD M.,LAYTON, MARK E.,KELLY, MICHAEL J., III,ANAND, RAJAN,JIAN, TIANYING,NANTERMET, PHILIPPE,ROECKER, ANTHONY J.,WON
申请号：
CA3008614
公开号：
CA3008614A1
申请日:
2016.12.15
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Disclosed are compounds of Formula A, or a salt thereof, where Q, X, R1 and R2 are as defined herein, which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating pain (acute, post-operative, neuropathic), or cough or itch disorders using the same.
