A method of processing soft tissue and skin using supercritical fluids is disclosed. The method comprises placing the soft tissue or skin on a scaffold in a processing chamber, adding supercritical fluid to the processing chamber, and pulsing the supercritical fluid in the processing chamber. A processing system for processing soft tissue and skin using supercritical fluids in accordance with the present invention comprises a processing chamber for housing the soft tissue, a scaffold, a vat for storing a processing fluid, a pump, a heating element, and a flow path.
