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PROCESS FOR DEMINERALIZATION OF BONE MATRIX WITH PRESERVATION OF NATURAL GROWTH FACTORS
专利权人:
Nancy J. Shelby;Kelly R. Kirker;Michael Mansfield;Steven M. Scott;Gregory A. Juda;Benjamin P. Luchsinger;Darrel L. Holmes
发明人:
Nancy J. Shelby,Steven M. Scott,Benjamin P. Luchsinger,Gregory A. Juda,Kelly R. Kirker,Darrel L. Holmes,Michael Mansfield
申请号:
US14186993
公开号:
US20140170232A1
申请日:
2014.02.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process.
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