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Positively charged copolymers for use as antimicrobial agents
专利权人:
AARHUS UNIVERSITET;Region Midtjylland
发明人:
JENSEN, Thomas Vorup,CHRISTIANSEN, Stig Hill,PETERSEN, Jørgen Eskild
申请号:
DK15770442
公开号:
DK3185882T3
申请日:
2015.08.28
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The present invention provides a positively charged co-polymer for use as an antimicrobial agent, wherein said positively charged co-polymer is composed of amino acids and/or derivatives thereof and wherein at least 75 molar percent of said amino acids are selected from the group consisting of alanine, lysine, glutamate, arginine and tyrosine and/or derivatives thereof. The present invention also provides methods for treating, preventing or ameliorating a microbial infection comprising administration of positively charged random co-polymers as well as a pharmaceutical composition comprising said co-polymer. The invention further provides a kit of parts comprising the positively charged random co-polymer.
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