Andrew Lurie Salzman;Shlomo Magdassi;Katrin Margulis-Goshen
发明人:
Andrew Lurie Salzman,Shlomo Magdassi,Katrin Margulis-Goshen
申请号：
US13575388
公开号：
US20130102591A1
申请日:
2011.01.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention provides compositions and methods for prevention, treatment, or management of pulmonary hypertension using piperidine, pyrrolidine, or azepane derivatives comprising one to four nitric oxide (NO) donor groups and a reactive oxygen species (ROS) degradation catalyst. The invention further provides a water dispersible powder comprising nanoparticles comprising said derivatives, as well as pharmaceutical compositions thereof and methods of use.
