Yissum Research Development Company of the Hebrew University of Jerusalem Ltd;Radikal Therapeutics Inc.
发明人:
Salzman, Andrew Lurie,Magdassi, Shlomo,Margulis-Goshen, Katrin
申请号：
AU2011210352
公开号：
AU2011210352A1
申请日:
2011.01.26
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention provides compositions and methods for prevention, treatment, or management of pulmonary hypertension using piperidine, pyrrolidine, or azepane derivatives comprising one to four nitric oxide (NO) donor groups and a reactive oxygen species (ROS) degradation catalyst. The invention further provides a water dispersible powder comprising nanoparticles comprising said derivatives, as well as pharmaceutical compositions thereof and methods of use.
