Kevin Lee,David Francis Tough,David Matthew Wilson
申请号:
US13500408
公开号:
US20120202875A1
申请日:
2010.10.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to methods for treatment or prevention of autoimmune and inflammatory diseases and conditions by inhibiting or modifying histone demethylation. In a further aspect the invention relates to a method for identifying agents useful in said methods of treatment. The invention particularly describes the role of certain histone demethylase enzymes in these diseases and conditions and their use as therapeutic and screening targets.