COMPOSES DE TETRAHYDROPYRIMIDODIAZEPINE ET DE TETRAHYDROPYRIDODIAZEPINE POUR LE TRAITEMENT DE LA DOULEUR ET DES AFFECTIONS ASSOCIEES A LA DOULEUR

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专利权人:

ESTEVE PHARMACEUTICALS; S.A.

发明人:

CUEVAS-CORDOBES, FELIX,ALMANSA-ROSALES, CARMEN

申请号：

CA3023379

公开号：

CA3023379A1

申请日:

2017.05.05

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention relates to new compounds of general formula (I) that show great affinity and activity towards the subunit a2d of voltage-gated calcium channels (VGCC), especially a2d-1 subunit of voltage-gated calcium channels or dual activity towards subunit a2d of voltage-gated calcium channels (VGCC), especially a2d-1 subunit of voltage-gated calcium channels, and noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments. (I)

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