The present invention relates to new compounds of general formula (1) that show great affinity and activity towards the subunit α26 of voltage-gated calcium channels (VGCC), especially α26-1 subunit of voltage-gated calcium channels or dual activity towards subunit α26 of voltage-gated calcium channels (VGCC), especially α26-1 subunit of voltage-gated calcium channels, and noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments.