BLAQUIERE NICOLE,DO STEVEN,DUDLEY DANETTE,FOLKES ADRIAN J.,HEALD ROBERT,HEFFRON TIMOTHY,JONES MARK,KOLESNIKOV ALEKSANDR,NDUBAKU CHUDI,OLIVERO ALAN G.,PRICE STEPHEN,STABEN STEVEN,WANG LAN,BLAQUIERE Nicole,DO Steven,DUDLEY Danette,FOLKES Adrian J.,HEALD Robert,HEFFRON Timothy,JONES Mark,KO
申请号:
SI201030536
公开号:
SI2483278T1
申请日:
2010.09.27
申请国别(地区):
SI
年份:
2014
代理人:
摘要:
The invention relates to benzoxazepin compounds of Formula I including stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z 1 is CR 1 or N; Z 2 is CR 2 or N; Z 3 is CR 3 or N; Z 4 is CR 4 or N; and B is a pyrazolyl, imidazolyl, or triazolyl ring which compounds have anti-cancer activity, and more specifically, inhibit PI3 kinase activity.