BLAQUIERE, NICOLE,DO, STEVEN,DUDLEY, DANETTE,FOLKES, ADRIAN,HEALD, ROBERT,HEFFRON, TIMOTHY,JONES, MARK,KOLESNIKOV, ALEKSANDR,NDUBAKU, CHUDI,OLIVERO, ALAN G.,PRICE, STEPHEN,STABEN, STEVEN,WANG, LAN
申请号：
HRP20140229
公开号：
HRP20140229T1
申请日:
2014.03.12
申请国别(地区):
HR
年份:
2014
代理人:
摘要：
The invention relates to benzoxazepin compounds of Formula I including stereoisomers, geometric isomers, tautomers, or pharmaceutically acceptable salts thereof, wherein: Z 1 is CR 1 or N； Z 2 is CR 2 or N； Z 3 is CR 3 or N； Z 4 is CR 4 or N； and B is a pyrazolyl, imidazolyl, or triazolyl ring which compounds have anti-cancer activity, and more specifically, inhibit PI3 kinase activity.
