COMPLEXES DE MÉTAUX DE TRANSITION PERMETTANT d'INHIBER LA RÉSISTANCE DANS LE TRAITEMENT DU CANCER ET DES MÉTASTASES

• 收藏
• 分享

专利权人:

ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)

发明人:

申请号：

EP07720131.7

公开号：

EP2016085B1

申请日:

2007.05.09

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention relates to organometallic compounds useful in the treatment of metastasis. The organometallic compounds comprise a ligand that is covalently bound to a bioactive compound, which is an inhibitor of a resistance pathway or a derivative thereof. Preferably, the organometallic compounds are half-sandwich (&ldquo；piano-stool&rdquo；) compounds. The compounds of the present invention offer a high variability with respect to the bioactive compound and to the nature of the ligand bound to a central transition metal.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/