Robert Beech,Gavi Begtrup,Jason Heikenfeld,Jacob A. Bertrand
申请号:
US16484989
公开号:
US20200155046A1
申请日:
2018.02.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a biofluid sensing device capable of concentrating a biofluid sample with respect to a target analyte, so that the analyte can be accurately detected or measured by EAB sensors. Methods for using such a device provide qualitative information about the presence of the analyte, and/or quantitative information about relative concentrations of the analyte in the biofluid. The disclosed device includes a concentration channel for concentrating the biofluid sample, as well as a selectively permeable membrane, one or more EAB sensors, and one or more secondary sensors carried on a water-impermeable substrate. A method for using the disclosed device to collect a biofluid sample, concentrate the sample relative to a target analyte, and measure the target analyte is also disclosed.