MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人:
Evanthia GALANIS,S. Keith ANDERSON,Cheyne B. KUROKAWA,Ianko D. IANKOV
申请号：
US16477830
公开号：
US20190365836A1
申请日:
2018.01.11
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This document provides methods and materials involved in treating cancer. For example, methods and materials for using an inhibitor of UFM1 activity or expression and/or an inhibitor of UFL1 activity or expression to reduce a cancer cell's ability to carry out a DDR, thereby increasing the sensitivity of cancer cells to treatment with a DNA damaging therapy such as radiation or chemotherapy, are provided.
