An active foam, which is made of natural rubber, a synthetic rubber or a synthetic resin containing a zirconium compound and/or a germanium compound, characterized in that it has a closed-cell structure and is used by directly or indirectly bringing it into contact with the human body upon drug administration is provided. By directly or indirectly bringing the active foam into contact with the human body, blood circulation can be promoted, the physical condition can be improved, or cure of a disease can be accelerated. Further, there is no side effect.