An active foam, which is made of natural rubber, a synthetic rubber or a syntheticresin containing a zirconium compound and/or a germanium compound, characterizedin that it has a closed-cell structure and is used by directly or indirectly bringingit into contact with the human body upon drug administration is provided. By directlyor indirectly bringing the active foam into contact with the human body, bloodcirculation can be promoted, the physical condition can be improved, or cureof a disease can be accelerated. Further, there is no side effect.