Celles for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells.

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专利权人:

CELLECTIS

发明人:

DUCHATEAU, Philippe,POIROT, Laurent

申请号：

NO20161276

公开号：

NO20161276A1

申请日:

2016.08.09

申请国别(地区):

NO

年份:

2016

代理人:

摘要：

Methods of developing genetically engineered immune cells for immunotherapy, which can be endowed with Chimeric Antigen Receptors targeting an antigen marker that is common to both the pathological cells and said immune cells (ex: CD38, CS1 or CD70) by the fact that the genes encoding said markers are inactivated in said immune cells by a rare cutting endonuclease such as TALEN, Cas9 or argonaute.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/