IMMUNOTHERAPY CELLS DESIGNED FOR TARGETING ANTIGEN PRESENT SIMULTANEOUSLY ON IMMUNE CELLS AND ON PATHOLOGICAL CELLS

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专利权人:

发明人:

申请号：

RU2016136702

公开号：

RU2016136702A3

申请日:

申请国别(地区):

RU

年份:

2018

代理人:

摘要：

Methods of developing genetically engineered immune cells for immunotherapy, which can be endowed with Chimeric Antigen Receptors targeting an antigen marker that is common to both the pathological cells and said immune cells (ex: CD38, CS1 or CD70) by the fact that the genes encoding said markers are inactivated in said immune cells by a rare cutting endonuclease such as TALEN, Cas9 or argonaute.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/