DÉRIVÉS DE PIPÉRIDINE EN TANT QUE MODULATEURS D'ACTIVITÉ DE RÉCEPTEUR DE CHIMIOKINE

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

申请号：

EP08796435.9

公开号：

EP2173714B1

申请日:

2008.07.23

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present application describes modulators of MIP-1 of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein m, Q, T, W, Z, R1, R3, R4, R5, R5a and R5b, are as set forth above. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using the modulators are disclosed.

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