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Piperidine derivatives as modulators of chemokine receptor activity
专利权人:
John Hynes;Joseph B. Santella;Daniel S. Gardner
发明人:
Joseph B. Santella,John Hynes,Daniel S. Gardner
申请号:
US12670025
公开号:
US08536198B2
申请日:
2008.07.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present application describes modulators of MIP-1 of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein m, Q, T, W, Z, R1, R3, R4, R5, R5a and R5b, are as set forth above. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using the modulators are disclosed.
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