Carlos Alemparte-Gallardo,David Barros-Aguirre,Monica Cacho-Izquierdo,Jose Maria Fiandor Roman,Jose Luis Lavandera Diaz,Modesto Jesús Remuiñan-Blanco
申请号:
US13144507
公开号:
US20120115899A1
申请日:
2010.01.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of Formula (I),wherein substituents R1, R2 and R5 are as defined, and Ar represents substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl substituted by a hydroxyalkyl substituent and an optional other substituent compositions containing them, their use in therapy, including their use as antibacterials, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.