DENIS BILLEN,TIMOTHY LEE STUK,VAGEESHA WARNAJITH LIYANA GUNAWARDANA,VALERIE SUE WESTRICK
申请号:
BR112018016708
公开号:
BR112018016708A2
申请日:
2017.02.07
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates to improved processes for the preparation of 7h-pyrrolo [2,3-d] pyrimidine, n-methyl-1- {trans-4- [methyl (7h-pyrrolo [2,3-d]) compound. pyrimidine-4-yl) amino] cyclohexyl} methanesulfonamide, its intermediates and their acceptable veterinary salts (formula (1)).a presente invenção refere-se a processos aprimorados para a preparação do composto 7h-pirrolo [2,3-d] pirimidina, n-metil-1- {trans-4- [metil (7h-pirrolo [2,3- d] pirimidina-4 -il) amino] ciclo-hexil} -metanossulfonamida, seus intermediários e seus sais veterinários aceitáveis (fórmula (1)).