GREGORY CHOPIUK,HA-SOON CHOI,PAMELA A. ALBAUGH,PAUL VINCENT RUCKER,YI FAN,ZHICHENG WANG
申请号:
BRPI0912668
公开号:
BRPI0912668A2
申请日:
2009.05.07
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Ros, KDR, FMS, C-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-IR, ALK4, ALK5 and ALK or combinations thereof.